Aminocaproic acid
Aminocaproic Acid (aminocaproic acid) is a small molecule pharmaceutical. Aminocaproic acid was first approved as Amicar on 1982-01-01. The pharmaceutical is active against plasminogen.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Aminocaproic acid (discontinued: Amicar, Aminocaproic, Aminocaproic acid)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Aminocaproic acid
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| AMINOCAPROIC ACID | Baxter | N-018590 DISCN | 1982-10-29 | 1 products |
| AMICAR | Epic Pharma | N-015229 DISCN | 1982-01-01 | 1 products, RLD |
| AMICAR | Hikma Pharmaceuticals | N-015197 DISCN | 1982-01-01 | 2 products, RLD |
| AMICAR | Hikma Pharmaceuticals | N-015230 DISCN | 1982-01-01 | 1 products, RLD |
Hide discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 28tak gum care tooth | unapproved drug other | 2018-07-17 |
| amicar | New Drug Application | 2022-06-28 |
| aminocaproic acid | ANDA | 2024-10-22 |
| bamboo salt eunganggo jook yeom toothpaste | OTC monograph not final | 2010-06-21 |
| clean breath tooth | unapproved drug other | 2021-11-30 |
| dr.el gum care tooth | unapproved drug other | 2019-09-25 |
| dr.lord green propol tooth | unapproved drug other | 2022-04-06 |
| greensaltrain tooth | unapproved drug other | 2021-11-30 |
| hae yan tooth | unapproved drug other | 2020-05-29 |
| hea yantoothpaste | unapproved drug other | 2023-04-23 |
Show 10 more
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| S0017 | Injection, aminocaproic acid, 5 grams |
Clinical
Clinical Trials
37 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemorrhage | D006470 | MP_0001914 | R58 | 1 | 2 | 1 | 3 | 5 | 12 |
| Fibrinolysis | D005342 | — | — | — | 1 | 1 | 1 | 2 | 4 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | — | — | 1 | 3 | 4 |
| Cardiopulmonary bypass | D002315 | — | — | — | 1 | 1 | 1 | 1 | 3 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | 1 | — | 1 | 1 | 3 |
| Scoliosis | D012600 | EFO_0004273 | M41 | — | — | — | 1 | 2 | 3 |
| Oral hemorrhage | D006472 | — | — | — | — | — | 1 | — | 1 |
| Arthritis | D001168 | HP_0001369 | M05-M14 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Inflammation | D007249 | MP_0001845 | — | 1 | 1 | 1 | — | 1 | 3 |
| Gingivitis | D005891 | HP_0000230 | K05.10 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Thrombocytopenia | D013921 | HP_0001873 | D69.6 | — | 1 | — | — | 1 | 2 |
| Craniosynostoses | D003398 | HP_0005458 | Q75.0 | 1 | 1 | — | — | — | 2 |
| Surgical blood loss | D016063 | — | — | — | 1 | — | — | — | 1 |
| Thrombosis | D013927 | — | — | — | 1 | — | — | — | 1 |
| Transfusion reaction | D065227 | — | D69.51 | — | 1 | — | — | — | 1 |
| Hematologic neoplasms | D019337 | — | — | — | 1 | — | — | — | 1 |
| Neoplasms | D009369 | — | C80 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cerebral hemorrhage | D002543 | — | — | 1 | — | — | — | 2 | 3 |
| Aortic diseases | D001018 | — | — | 1 | — | — | — | — | 1 |
| Rosacea | D012393 | — | L71 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart failure | D006333 | HP_0001635 | I50 | — | — | — | — | 2 | 2 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 2 | 2 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | — | 2 | 2 |
| Menorrhagia | D008595 | EFO_0003945 | N92.0 | — | — | — | — | 2 | 2 |
| Hemophilia a | D006467 | EFO_0007267 | D66 | — | — | — | — | 2 | 2 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 2 | 2 |
| Pneumonia | D011014 | EFO_0003106 | — | — | — | — | — | 2 | 2 |
| Hyperaldosteronism | D006929 | HP_0011736 | E26 | — | — | — | — | 2 | 2 |
| Pulmonary arterial hypertension | D000081029 | — | — | — | — | — | — | 2 | 2 |
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | — | — | — | 2 | 2 |
Show 75 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Aminocaproic acid |
| INN | aminocaproic acid |
| Description | 6-aminohexanoic acid is an epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator. It has a role as an antifibrinolytic drug, a hematologic agent and a metabolite. It is an epsilon-amino acid and an omega-amino fatty acid. It is functionally related to a hexanoic acid. It is a conjugate acid of a 6-aminohexanoate. It is a tautomer of a 6-aminohexanoic acid zwitterion. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | NCCCCCC(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 60-32-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1046 |
| ChEBI ID | 16586 |
| PubChem CID | 564 |
| DrugBank | DB00513 |
| UNII ID | U6F3787206 (ChemIDplus, GSRS) |
Target
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Aminocaproic acid
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 9,609 documents
View more details
Safety
Black-box Warning
Black-box warning for: Lisinopril
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
225 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use